Barça are slight favourites to edge Betis despite several absences, with a narrow win expected in what could be a tightly contested, high-tempo La Liga clash.
Real Betis host FC Barcelona in Seville on Saturday, with Betis riding a strong run of form, unbeaten in their last eight, at their temporary home during stadium renovations.
Despite their momentum, home-side injuries and doubts over key players such as Isco, Bellerín and Sofyan Amrabat may hamper their attack.
Barcelona arrive somewhat weakened, missing several regulars, but still pack firepower with the returning midfielders and their attacking trio set to test Betis’ defense.
The visitors remain favorites, with many analysts tipping a narrow win, citing their tactical discipline and individual quality.